Oligopeptide-34 key effects include:
Brightening and Spot Reduction:
Oligopeptide-34 reduces melanin production by downregulating TRP-1, TRP-2, MITF, and tyrosinase; blocks the assembly of melanosomes and their transfer to keratinocytes; and activates the breakdown of melanocyte-stimulating hormone (MSH). Studies show it can significantly lower tyrosinase activity (by about 65%) and is more effective at reducing pigmentation than traditional vitamin C and arbutin.
Anti-Inflammatory Effect:
By downregulating TH1-type pro-inflammatory cytokines and reducing dermal lymphocyte proliferation, Oligopeptide-34 delivers a noticeable anti-inflammatory effect.
Anti-Aging and Firming:
Oligopeptide-34 promotes fibroblast division and differentiation, significantly increasing levels of collagen, elastin, and fibronectin in the extracellular matrix (ECM), achieving a firming and anti-aging effect.
