Acetyl Hexapeptide-37 is commonly sold under the brand name Diffuporine. Its role in skin hydration mainly lies in "promoting internal water transport and supporting the skin barrier," rather than simply attracting moisture on the surface like glycerin or hyaluronic acid.
How is Acetyl Hexapeptide-37 different from common moisturizing ingredients?
Hyaluronic acid, glycerin, butylene glycol: Mainly hydrate by attracting and holding water on the skin's surface or in the stratum corneum.
Ceramides, cholesterol, fatty acids: Focus on barrier repair to reduce water loss.
Acetyl Hexapeptide-37: Leaning more towards "aquaporin-regulating hydration," it helps water move more evenly between different layers of the skin by boosting AQP3-related pathways, while also supporting the barrier.
