Palmitoyl Tetrapeptide-20: Expanding From Skincare And Anti-aging To Hair Pigment Management

Jul 06, 2026

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Beyond its traditional uses in skincare for antioxidant and anti-wrinkle purposes, recent scientific research has uncovered the potential of palmitoyl tetrapeptide-20 in hair care.

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As an α-msh (alpha-melanocyte-stimulating hormone) agonist, palmitoyl tetrapeptide-20 can protect the function of hair follicle melanocytes and reduce oxidative stress inside cells by boosting catalase expression, thereby activating the melanogenesis process.

 

This finding suggests that the ingredient has potential cosmetic applications in delaying hair graying (canities) and promoting hair pigmentation.

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