
Product Information
|
Product Name |
Acetyl Hexapeptide-8 |
|
Reference |
Argireline, AHP-8 |
|
CAS NO. |
616204-22-9 |
|
Molecular Formula |
C34H60N14O12S |
|
Molecular Weight |
888.99 |
|
Structure |
|
|
Sequence |
Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 |
|
Quality document |
Coa, TDS, MSDS and etcs |
|
Package |
1.0g, 10.0g, 50.0g, 100.0g |
|
Storage |
Keep in a cool, dry place, Long time storage at-20℃. |
Specifications
|
Purity |
≥98.0% |
|
Appearance |
White powder |
|
Solubility |
Water soluble |
|
Heavy Materials |
≤10ppm |
|
Loss on drying |
≤5.0% |
|
Total Yeast and Mold Count |
<10 CFU/ml |
|
Bacterial Endotoxins |
≤5EU/mg |

Descriptions
Acetyl hexapeptide-8 is a synthetically produced short-chain peptide composed of six amino acids. It is widely known as a Botox-like peptide in the cosmetics industry.
Acetyl hexapeptide-8 is inspired by the mechanism of action of Botulinum Toxin, but it exerts its effects by mimicking the N-terminal fragment of the natural protein SNAP-25 rather than cleaving proteins like botulinum toxin.
Compared with injectable botulinum toxin, acetyl hexapeptide-8 has extremely high safety, no neurotoxicity, does not cause complete facial muscle paralysis, and has minimal side effects. It is currently one of the most widely used and thoroughly researched anti-wrinkle peptides in the world and is commonly used in high-end anti-aging skincare products.

Evaluation Of Efficacy
Acetyl hexapeptide-8 In vivo test
The effective rate of anti-wrinkle is between 30% and 50%, the best effective performance after 14 days.

Applications
Acetyl hexapeptide-8 is used in kinds of skincare products.
Facial serums: Added at high concentrations as a core anti-aging ingredient, providing intensive care for local wrinkles.
Creams and lotions: Used as a daily anti-aging maintenance ingredient, applied to the entire face.
Eye creams or eye masks: Specifically targeting the delicate skin around the eyes and easily formed crow's feet and fine lines.
Neck cream: Aimed at improving horizontal neck lines (neck wrinkles).
Face masks: effects both immediate and cumulative anti-wrinkle effects.
Aesthetic repair products: Used during the maintenance period after Botox injections to extend aesthetic results.

Formulation Guidelines
Recommended use level: 0.01%-0.2%
pH Range: 5.0 - 7.0.
Compatible with most moisturizers (glycerin, hyaluronic acid), thickeners, and preservatives.
Can be combined with other peptides such as copper peptides (GHK-Cu) and palmitoyl pentapeptide-4 to get better skincare effects.
Can be used with retinol (Vitamin A) and vitamin C derivatives, but attention must be paid to the overall stability of the formulation and irritation control.
Safety Regulations
Acetyl hexapeptide-8 complies with China's "Cosmetic Safety Technical Specifications", EU CosIng, and US FDA cosmetic raw material lists.

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