
Product Information
|
Product Name |
Pentapeptide-18 |
|
CAS NO. |
64963-01-5 |
|
Chemical Formula |
C29H39N5O7 |
|
Molecular Weight |
569.65 |
|
Sequence |
H-Tyr-D-Ala-Gly-Phe-Leu-OH |
|
Chemical Structure |
|
|
Product Grade |
Technical grade, cosmetic grade |
|
Quality document |
Coa, TDS, MSDS and etcs |
|
Package |
1.0g, 10.0g, 50.0g, 100.0g |
|
Storage |
Keep in a cool, dry place, Long time storage at-20℃. |
Specification Index
|
Specification |
≥98.0% |
|
Appearance |
White powder |
|
Solubility |
Water soluble |
|
Heavy Materials |
≤10ppm |
|
Loss on drying |
≤5.0% |
|
Total Yeast and Mold Count |
< 10 CFU/ml |
|
Bacterial Endotoxins |
≤5EU/mg |
Descriptions
Pentapeptide-18 is a synthetic pentapeptide that has attracted attention in the cosmetic field. It is regarded as a gentle, non-invasive botox-like ingredient with its unique mechanism of action and significant anti-wrinkle effects.

Mechanism of Action
Pentapeptide-18 is a neurotransmitter-inhibiting peptide, commonly referred to as a 'neuropeptide. By reducing muscle contractions that cause dynamic wrinkles at the source, pentapeptide-18 can effectively smooth and prevent the formation of expression lines.

Efficacy and Applications
Studies have shown that pentapeptide-18 alone can significantly reduce wrinkle depth, particularly in the eye and forehead areas.
Synergistic effect:
When combined with Acetyl Hexapeptide-8 , the two peptides can produce a strong synergistic effect. They act on different steps of muscle contraction, and their combined use can reduce wrinkle depth by nearly 50%, far exceeding the effect of using either one alone.
Improving skin texture:
Besides anti-wrinkle effects, pentapeptide-18 has moisturizing benefits and can improve skin firmness.
Brightening skin tone:
Research indicates that Pentapeptide-18 can also help lighten dark spots and other uneven skin tone issues.

Formulation Guide
Commanded Concentration: 0.05%-0.10%
Good Partner:
Strongly recommended to be mix used with Acetyl Hexapeptide-8 to achieve the best effect in reducing dynamic wrinkles.
Applicable Product Types:
Pentapeptide-18 is suitable for various anti-aging skincare products, especially serums, eye creams, face creams, and masks targeting areas with frequent expression lines ,particularly around the eyes and forehead.
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