Mechanism of Action of Minoxidil
Minoxidil works by dilating the blood vessels in the scalp to increase blood flow to the hair follicles, supplying them with more oxygen and nutrients. This helps extend the hair growth 'anagen phase' and speeds up the transition from the 'telogen phase' to the growth phase.
Specifically, the mechanism of action of minoxidil can be broken down into the following steps:
Promoting blood vessel dilation in hair follicles: Minoxidil increases local blood flow, creating a better growth environment for the follicles.
Activating potassium channels: Minoxidil acts as a potassium channel opener, helping to boost the activity of hair follicle cells.
Stimulating follicles to enter the growth phase: During the growth phase, hair grows faster and becomes denser.
Usage and Effectiveness
Minoxidil is usually applied directly to the scalp in the form of a liquid or foam. Common concentrations are 2% and 5%, with 5% usually recommended for men and 2% for women. Using it twice a day, morning and night, can give the best hair growth results.
Within 4 weeks of use: Hair follicles gradually enter the growth phase, but hair shedding may temporarily increase as older hair is replaced by new healthy strands.
· 3-6 months of use: Most users will start to notice noticeable hair growth improvements, especially on the crown and hairline.
· 6-12 months of use: The effects become more obvious, with hair in thinning areas becoming thicker and denser.
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