Bfgf Growth Factor
bFGF has a wide range of effects on almost all cells related to trauma, such as fibroblasts, vascular endothelial cells, smooth muscle cells, epithelial cells, chondrocytes and nerve cells.
Description
Product Names: Bfgf Growth Factor
Other name: Fibroblast Growth Factor FGF,bFGF,Sh-Polypeptide-1
Molecular Formula.:C62H95N15O15
Purity: 98% rh-bFGF
Mol. Wt.: 16.0 kDa
Resources: Escherichia coli (E. coli)
Purity: ≥98.0% by SDS-PAGE analysis
Storage Condition: -20 oC
Grade: Cosmetic and pharmaceutical
Storage Duration: 3 years
Appearance:White powder rh-bFGF
Product specifications: 1mg/Vials,5mg vials
Bfgf Growth Factor package in bottles
Descriptions
Bfgf Growth Factor, also known as bFGF and FGF2, is a member of the fibroblast growth factor family. There are two inhibitors which affect the actions of FGF2: PD 173074 and SU 5402. PD 173074 is an inhibitor of FGFR1. It can potently and selectively antagonize the neurotrophic and neurotropic actions of FGF-2. Nanomolar concentrations of PD 173074 preventes FGF2, but not insulin-like growth factor-1, support of cerebellar granule neuron survival under conditions of serum/K(+) deprivation. As an inhibitor of FGF2, SU 5402 is effective only at a 1,000-fold greater concentration. PD 173074 and SU 5402 show 1,000-fold differential IC(50) values for inhibition of FGF2-stimulated neurite outgrowth in PC12 cells and in granule neurons, and FGF2-induced mitogen-activated protein kinase (p44/42) phosphorylation. The two inhibitors fail to disturb downstream signalling stimuli of FGF2. PD 173074 represents a valuable tool for dissecting the role of FGF2 in normal and pathological nervous system function without compromising the actions of other neurotrophic factors.
Features
No animal origin: the product is free of animal virus, no pathogenic substances, no external factor pollution, and high safety.
High purity: SDS-PAGE purity reached 98%.
High biological activity: 1 x 10^7 IU per 1 mg of protein.
Use a small amount of protein to achieve the desired experimental results.
Stability: This product is a lyophilized powder containing bioactive protective agent. It has been mass-produced and the difference between batches is small.
Bfgf Growth Factor Product Properties
Expression system: E.coli
Appearance: White or off-white lyophilized powder
Purity≥98%(SDS-PAGE)
Specific activity ≥1 x 10^7 U/mg pro.
Molecular weight 17 KD±1.7KD
Endotoxin< 0.2 EU/μg
Bfgf Growth Factor Biological activity:
The biological activity of the mouse fibroblast cell line BALB/3T3 was determined by the method of Chinese Pharmacopoeia 2015 edition using bFGF.
Application
It can be used for cell culture to enhance cell proliferation, cell growth and cell differentiation.
Bfgf Growth Factor Usage
It is recommended to centrifuge the powder immediately before opening the lid to sink the powder to the bottom of the tube, then dissolve it in sterilized deionized water to prepare a storage solution of 100 μg/ml. It can be stored stably for 1 week at 2 °C ~ 8 °C. When diluted to a lower concentration (not less than 10 μg/ml), 0.1% BSA or HSA is required. If it is necessary to extend the storage time, it is recommended to freeze at -70 ° C or -20 ° C. It is not recommended to repeat freezing and thawing.
Transportation and storage Stability
Transport stability:It is transported in an ice pack to keep it active.
Storage stability:It is stored at -15 ° C to -20 ° C to ensure stability within 24 months.
Mobelbio .,llc factory view:
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Disclaimer:
The product is in chemical form , just for laboratary research ,industry production and professional use only,forbidden for personal use directly.
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