Cibinetide

Product Name: Cibinetide
Other Names: ARA 290, Pyroglutamate Helix B Surface Peptide, pHBSP
Sequence:Glp-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH (Glp is pyroglutamic acid)
CAS#: 1208243-50-8 (free base)
Chemical Formula: C51H84N16O21
Exact Mass: 1,256.60
Molecular Weight: 1,257.320
Activity:
Erythropoietin/CD131 heteroreceptor agonistetide
Solubility > 50 mg per ml in water

Purity: ≥99.0%
Appearance: White powder

Description:

Cibinetide, also known as ARA-290, is a synthetic 11-mer peptide that binds the tissue-protective receptor. ARA290 inhibits high glucose-induced apoptosis of NRK-52E cells.

Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation. Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain. ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception.

Disclaimer: The product are for laboratary research use only.

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