Desmopressin
Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities
Description
Product Name : Desmopressin
Synonyms:(Deamino-Cys1,D-Arg8)-Vasopressin, DDAVP, Desmopresina; Desmopressinum
CAS No#:62288-83-9
Molecular Formula: C46H64N14O12S2
MW: 1069.23
Sequence:3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bond)
Appearance: white powder
Purity (HPLC):≥98.0%
Single Impurity (HPLC): ≤2.0%
Acetate Content(HPLC): 5.0%-12.0%
Water Content (Karl Fischer): ≤10.0%
Peptide content: ≥80.0%
Package:1g-1kg in plastic bottle
Description
Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).
Desmopressin (DDAVP) is a selective agonist for the vasopressin V2 receptor (V2R), which is coupled to cAMP-dependent signaling. DDAVP induces cAMP-dependent eNOS activation via Ser1177 phosphorylation. DDAVP (at doses ranging from 100 ng/ml to 1 μg/ml) exerts a modest but significant antiproliferative effect on cultured CT-26 and Colo-205 cells.
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