Monobenzone
Monobenzone is an organic compound which used as a topical drug for drug-induced depigmentation.
Description
Product Name: Monobenzone
Chemical name: 4-Benzyloxyphenol
CAS NO.103-16-2
EINECS:203-083-3
Molecular formula.C13H12O2
Molecular Weight 200.24
Purity: 99.0%
Monobenzone structure:
Grade: pharmaceutical grade
Standard: BP/USP
Appearance: White crystalline powder
Shelf life ：24 Months
Standard Package: 25KG/drum,Double Aseptic food poly bags inside,Paper Drums outside.
Sample Package: Aluminum foil bag.
Quantity Less than 50kgs, Recommend to take by DHL,UPS,TNT,EMS,Fedex.
Quantity More than 200kgs, Recommend to take Sea Shipment.
Lead Time: By Express Courier, around 4 to 7 days.
By Air, around 5 to 8 days
By Sea, around 10 to 30days
Introduction
Monobenzone is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. It is a colourless solid that is classified as the monobenzyl ether of hydroquinone. Monobenzone is soluble in alcohol, benzene, and diethyl ether, and practically insoluble in water.
Function
The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes. Therefore, monobenzone is used as a topical medicine to permanently depigment normal skin surrounding vitiliginous lesions only in patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo. Monobenzone is also being considered for the treatment of Melanoma.
Used in cosmetics
Monobenzone is a compound used as a topical drug for medical depigmentation.
The topical application of monobenzone powder in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
It may cause destruction of melanocytes and permanent depigmentation.
The histology of the skin after depigmentation with topical monobenzone powder is the same as that seen in vitiligo.The epidermis is normal except for the absence of identifiable melanocytes.
It is also used to derive dyes for fiber dyeing and is used in the rubber industry.
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