L-Glutathione Powder
L-Glutathione also know as Glutathione is a peptide found in plants and animals. It is a powerful antioxidant produced by the liver to protect the body against free radicals, peroxides, and heavy metal.
Description
Product Name: L-Glutathione Powder
CAS No. 70-18-8
EINECS No. 200-725-4
Molecular formula: C10H17N3O6S
Molecular weight: 307.3235
Structure:
The melting point of 182-192 °CC
Rotation - 16.5 °C(c = 2, H2O)
Solution:Water soluble
Purity(HPLC) ≥99.0%
Grade : pharmaceutical Grade
Standard: BP/EP/USP
Appearance: White powder
Packing : 10kg/Carton, 20kg/Carton
Storage: Keep dry and away from light and stored in ventilated cool library.
L-Glutathione Tecnical Data
Appearance: White crystalline powder
Solubility: Easily soluble in water, slightly solube in ethanol
Specific rotation: -15.5°~-17.5° ([α]D20)
Heavy metals: ≤10mg/kg
As: ≤2mg/kg
NH4: ≤200mg/kg
Chloride: ≤200mg/kg
Sulfate: ≤300mg/kg
Fe: ≤10mg/kg
Loss on drying: ≤0.5%
Ash: ≤0.1%
Mechanism of action
L-Glutathione powder,Glutathione (GSH) is a short peptide composed of three amino acid residues that can be naturally produced in human cells. They are glutamic acid, cystine and glycine. The structural formula is as shown in the figure below.
The main functional group of glutathione is sulfhydryl (-SH), which can be oxidized into -S-S-bond (disulfide bond), and -S-S-bond is converted into sulfhydryl after reduction. Many enzymes, especially those related to protein conversion, have a major impact. Because the human body is constantly undergoing oxidation and reduction reactions during its life activities, and oxidation reactions will produce free radicals. Excessive free radicals can damage the body and are also an important factor leading to aging.
In order to eliminate excessive free radicals, the body has a set of antioxidant network, which is composed of vitamin C, vitamin E, glutathione, ubiquinone (Co. Q10), lipoic acid, nicotinamide, etc. They form a network with each other to work together: Vitamin E scavenges free radicals and becomes oxidized vitamin E, and vitamin C can regenerate vitamin E. After regeneration, vitamin C becomes dehydroascorbic acid, and glutathione can turn dehydroascorbic acid into vitamin C, that is, vitamin C can also be regenerated by glutathione.
It can be seen that if glutathione is not enough, it will affect the regeneration of vitamin C. If the amount of vitamin C is not enough, it will affect the regeneration of vitamin E. If vitamin E is not enough, the cell membrane will suffer. It has the most extensive effects in the human body and is greater than any nutrient. It has good antioxidant properties, that is, it can reduce cell aging and promote cell synthesis.
Applcations
L-Glutathione plays a vital role in the antioxidant system in the body, and antioxidant is related to a variety of processes, including aging, melanin synthesis, cell damage, inflammation, etc., so it is multi-functional for glutathione. Of course, the cosmetics industry is extremely welcome.
Whitening mechanism
L-Glutathione Powder can directly inhibit the activity of tyrosinase, and at the same time can sweep away a large number of oxidative free radicals, prevent free radicals from activating tyrosinase, and can also be hydrolyzed into cysteine, which interferes with the synthesis of melanin. In other words, in the whitening process, it has the dual effects of "anti-oxidation" + "inhibition" at the same time. (1 ingredient for 2 jobs, very good~)
L-Glutathione Powder is also a small molecule peptide with a molecular weight of 307 daltons (molecules greater than 500 daltons cannot cross the skin barrier). This means that the glutathione applied on the skin can be absorbed by the skin. Moreover, it is also an anti-oxidant component in human cells, which makes it easier to "deceive" the defense layer and enter the human body more easily.
Human glutathione GSH content-age curve
People will gradually become old with the loss of glutathione, so it is very popular to delay the aging of human body by eating glutathione health products.
Therefore, because glutathione has the ability of "anti-oxidation" + "inhibition" against melanin, and has the physical properties of small molecular weight, as long as the skin care products containing high enough concentration of glutathione (except facial cleanser, etc.) ) It can be effectively whitened by directly rubbing on the skin.
There are also many whitening injection formulas of medical and aesthetic institutions that are glutathione, which can achieve the effect of natural whitening and translucent skin after use.
Fight inflammation and allergies
L-Glutathione is also related to allergies. Chinese researchers Zhao Xinling and others have tested the in vitro anti-allergic activity of glutathione and found that it can be anti-allergic. Its effects include inhibition of hyaluronidase and inhibition of delayed-type allergic reactions. The effect at a concentration of 5mg/ml can be compared with puhl. Min has the same effect
Detoxification effect
L-Glutathione can relieve exogenous and endogenous toxins. This is because its structure contains an active sulfhydryl group -SH, which is easily oxidatively dehydrogenated. This special structure makes it the main free radical scavenger in the body, which can purify the internal environment by scavenging free radicals.
The "effectiveness" of glutathione needs to be based on the premise of "activity". The biggest problem when using it is that the "activity" is difficult to preserve. Its major disadvantage is that it is unstable in aqueous solution and needs to be used. Special preparations or production forms are used to solve the problem, such as the use of dry and wet separation packaging technology, encapsulation technology, freeze-drying technology, etc. to solve the stability problem, so most of the glutathione on the market is in ampoules or frozen Appears in dry powder form.
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