Compstatin

Product name: Compstatin
Synonyms: ICVVQDWGHHRCT-NH2 (Disulfide bridge: Cys2-Cys11), Compstatin
CAS No.:206645-99-0
Sequence: H-Ile-Cys-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys11)
Molecular Formula: C66H99N23O17S2
Molecular Weight: 1550.77
Purity (HPLC) ≥98.0%
Appearance: White powder

Compstatin structure:

Packaging & Shipping:
Low-temperature, vacuum-packed, accurate to milligrams upon request.
Compstatin Specifications
Acetate content≤ 12.0%
Moisture content≤8.0%
Peptide content≥80.0%
Endotoxin≤ 50EU/mg
Amino acid composition analysis≤± 10%

Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.

Descriptions:
Camprestatin is a specific inhibitor peptide with strong stability, and the N-terminus of the sequence is acetylated, which can effectively prevent the peptide from being degraded by enzymes in organisms. The main physiological function of kamp statin is to be able to completely inhibit heparin/protamine-induced complement activation without side effects on heart rate or systemic vascular, central venous and pulmonary artery pressure, and at the same time, kamp statin is a safe and effective complement inhibitor with the potential to inhibit complement activation in clinical cardiac surgery. In terms of peptide synthesis, kampramatin belongs to the polypeptide with high yield.

Note: For research purposes only, not for human use

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