Larazotide Acetate
Larazotide Acetate is a synthetic peptide drug used to treat celiac disease.
Description
Product name: Larazotide Acetate
Aliases: AT-1001
Chemical name: Lazotide acetate
CAS Number: 349085-85-4
Molecular Formula: C₃₈H₆₂N₁₂O₁₂
Molecular weight: 878.98 g/mol
Purity: 98.0% (By HPLC)
Appearance: White Powder
Min orders: 1g
Descriptions
Larazotide Acetate is a synthetic peptide drug used to treat celiac disease. It reduces intestinal permeability by inhibiting the opening of tight intestinal junctions, thereby blocking gluten-triggered immune responses. Larazotide Acetate is the first celiac disease treatment to enter clinical trials with potential therapeutic and prophylactic effects.
Mechanism of action:
Larazotide Acetate prevents transepithelial transport of gluten peptides and subsequent immune responses by inhibiting the zonulin signaling pathway, reducing the opening of tight junctions between intestinal epithelial cells and decreasing intestinal permeability.
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