Kisspeptin-10
Kisspeptin-10 triggers a series of signaling pathways by binding to GPR54 receptors in the hypothalamus, ultimately leading to the release of gonadotropin-releasing hormone (GnRH).
Description
Product Name: Kisspeptin-10
CAS No.: 388138-21-4
Amino acids sequence: H-Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Chemical Formula: C258H401N79O78
Molecular Mass: 5857
Synonyms: KISS-1 (68-121), Protein KISS-1, Gene KISS1 protein
CAS Number: 388138-21-4
Purity: >98.0%
Appearance: White powder
Kisspeptin-10 is a peptide hormone in the Kisspeptin family that consists of 10 amino acids. Kisspeptin is an active fragment produced by enzymatic digestion of a precursor protein encoded by the KISS1 gene, with Kisspeptin-10 being the shortest and biologically active form. Kisspeptin plays a key role in regulating the reproductive system and sex hormone secretion, primarily by activating the GPR54 receptor (also known as the Kisspeptin receptor) in the hypothalamus.
Mechanism of action:
Kisspeptin-10 triggers a series of signaling pathways by binding to GPR54 receptors in the hypothalamus, ultimately leading to the release of gonadotropin-releasing hormone (GnRH). GnRH further stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which regulate the secretion of sex hormones such as testosterone and estrogen. This process is essential for the development and function of the reproductive system.
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